Clinical studies also suggest potential therapeutic applications for cannabinoids in aging populations
Cannabinoids hold promise for improving health and promoting longevity of older populations, according to the findings of a systematic review published in the Journal of Cannabis Research.
British researchers reviewed findings from 11 preclinical studies and seven human trials assessing the impact of cannabinoids, particularly CBD and THC, on older populations.
“THC enhances memory, reduces inflammation, and offers neuroprotection, while CBD extends lifespan, improves motility, and promotes autophagy in preclinical models,” investigators reported. “Both cannabinoids highlight potential for longevity and cognitive resilience, though careful dosing is crucial to minimize risks.
“Additionally, their combined antioxidant and anti-inflammatory properties might offer synergistic benefits for healthy aging. … Clinical studies also suggest potential therapeutic applications for cannabinoids in aging populations, although further research is needed to understand their mechanisms of action and long-term effects fully.”
The study’s authors concluded: “Cannabinoids hold promise for supporting healthy aging and enhancing the quality of life in older populations. While preliminary research suggests intriguing possibilities, more studies are needed to solidify the link between cannabis use, the ECS [endocannabinoid system], and healthy aging in humans.”
Survey data indicates that as many as one in five older adults consume cannabis products, with most saying that it improves their overall quality of life.
This summary was republished from NORML. Full text of the study, “The impact of cannabis use on aging and longevity: A systematic review of research insights,” appears in the Journal of Cannabis Research. Additional information is available from the NORML Fact Sheet, ‘Cannabis Use by Older Adult Populations.’
